Aquaculture refers to the breeding, rearing, and harvesting of animals and plants in water environments. The global aquaculture production is steadily increasing at an impressive rate. Increasing global population coupled with increased per capita seafood consumption result in constant, growing demand for seafood. Singapore seafood consumption has been 22.0 kg annually per capita and is higher than global average which is 18.8kg. Being a small nation with limited land resource, we are also concerned about our fish supplies as we bring in 90% of our food imports. Thus, science based sustainable and profitable aquaculture is very important for economic concerns and environment. Fast detection of diseases and proper treatment reducing antimicrobial resistance in aquaculture are also essential for fish and human health.